1219794-61-2 Usage
Uses
Used in Research Applications:
Lignoceric acid-d47 is used as an isotopically labeled compound for various research purposes. The incorporation of deuterium isotopes allows for the study of metabolic pathways, enzyme interactions, and other biological processes involving fatty acids. lignoceric acid-d47 can be particularly useful in tracing the fate of fatty acids in cellular metabolism and understanding their role in various physiological and pathological conditions.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, lignoceric acid-d47 can be used as a starting material for the synthesis of deuterated drug candidates. The deuterium-labeled compounds may exhibit altered pharmacokinetic and pharmacodynamic properties compared to their non-deuterated counterparts, potentially leading to improved drug efficacy and reduced side effects.
Used in Analytical Chemistry:
Lignoceric acid-d47 can be employed as an internal standard or a reference compound in analytical chemistry, particularly in mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy. The presence of deuterium isotopes can help in the accurate quantification and identification of target analytes, improving the precision and reliability of analytical results.
Used in Biochemical Studies:
In biochemical research, lignoceric acid-d47 can be utilized to study the mechanisms of fatty acid metabolism, transport, and storage. The deuterium-labeled compound can be used to investigate the role of specific enzymes and transporters in the metabolism of long-chain fatty acids, providing insights into the regulation of lipid homeostasis and its implications in health and disease.
Used in Nutritional Science:
Lignoceric acid-d47 can be applied in nutritional science to study the消化吸收 (absorption and metabolism) of long-chain fatty acids in the human body. This information can be valuable for developing targeted nutritional interventions and understanding the impact of dietary fatty acids on health and disease.
Check Digit Verification of cas no
The CAS Registry Mumber 1219794-61-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,9,7,9 and 4 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1219794-61:
(9*1)+(8*2)+(7*1)+(6*9)+(5*7)+(4*9)+(3*4)+(2*6)+(1*1)=182
182 % 10 = 2
So 1219794-61-2 is a valid CAS Registry Number.
1219794-61-2Relevant academic research and scientific papers
Sonnenberger, Stefan,Lange, Stefan,Langner, Andreas,Neubert, Reinhard H.H.,Dobner, Bodo
, p. 531 - 542 (2016)
The synthesis of 12 deuterated ceramides with either a deuteration at the last carbon atom of the amide bound fatty acid or a perdeuterated fatty acid chain is described. The ceramides were prepared starting from sphingosine or phytosphingosine and ω deuterated or perdeuterated fatty acids with PyBOP as activating agent in high yields. For the synthesis of the specifically deuterated fatty acids, dicarboxylic acids were transformed into ω deuterated alkyl bromide, which was chain elongated with blocked ω bromo alcohols by copper catalyzed Grignard coupling. Oxidation of regenerated alcohol function yields the ω deuterated fatty acids.
