1219813-78-1

Basic information

• Product Name: 3-(2-BroMo-acetyl)-piperidine-1-carboxylic acid tert-butyl ester
• Synonyms: tert-Butyl 3-(2-broMoacetyl)piperidine-1-carboxylate;tert-Butyl 3-(2-bromoacetyl);1-Piperidinecarboxylic acid, 3-(2-bromoacetyl)-, 1,1-dimethylethyl ester;3-(2-BroMo-acetyl)-piperidine-1-carboxylic acid tert-butyl ester
• CAS NO: 1219813-78-1
• Molecular Formula: C₁₂H₂₀BrNO₃
• Molecular Weight: 306.1961
• EINECS: -0
• Mol File: 1219813-78-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 367.7±32.0 °C(Predicted)
• Appearance: /
• Density: 1.336±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -2.69±0.40(Predicted)
• CAS DataBase Reference: 3-(2-BroMo-acetyl)-piperidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-BroMo-acetyl)-piperidine-1-carboxylic acid tert-butyl ester(1219813-78-1)
• EPA Substance Registry System: 3-(2-BroMo-acetyl)-piperidine-1-carboxylic acid tert-butyl ester(1219813-78-1)

Safety Data

• Hazardous Substances Data: 1219813-78-1(Hazardous Substances Data)

Usage

Uses

tert-Butyl 3-(2-Bromoacetyl)piperidine-1-carboxylate is used as a reactant in the synthesis of oxazolobenzimidazole derivatives and analogs as potentiators of metabotropic glutamate receptors.

Relevant articles and documents

OXAZOLOBENZIMIDAZOLE DERIVATIVES

The present invention is directed to oxazolobenzimidazole derivatives which are potentiators of metabotropic glutamate receptors, particularly the mGluR2 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which metabotropic glutamate receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which metabotropic glutamate receptors are involved.