1219835-06-9Relevant academic research and scientific papers
Straightforward synthesis of ethers: Metal-free reductive coupling of tosylhydrazones with alcohols or Phenols
Barluenga, Jose,Tomas-Gamasa, Maria,Aznar, Fernando,Valde, Carlos
supporting information; experimental part, p. 4993 - 4996 (2010/09/08)
(Figure Presented) Ethers made easy: Heating a solution containing a tosylhydrazone and either a phenol or an alcohol in the presence of K 2CO3 leads to the corresponding ethers (see scheme; MW=microwave, Ts=tosyl). The reaction is fairly general for the preparation of aryl alkyl and alkyl alkyl ethers, and represents a new method for the reductive etherification of carbonyl compounds.
