1219957-80-8 Usage
Also known as
GNE-892
Chemical structure
pyrimidine derivative with a chloro group and a pyridinylmethyl substituent
Function
potent and selective small molecule inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2)
Mechanism of action
inhibits SGLT2, leading to lower blood glucose levels by promoting urinary excretion of excess glucose
Potential applications
treatment of type 2 diabetes and other glucose-related disorders, drug discovery and development for new therapeutic agents targeting SGLT2
Check Digit Verification of cas no
The CAS Registry Mumber 1219957-80-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,9,9,5 and 7 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1219957-80:
(9*1)+(8*2)+(7*1)+(6*9)+(5*9)+(4*5)+(3*7)+(2*8)+(1*0)=188
188 % 10 = 8
So 1219957-80-8 is a valid CAS Registry Number.
1219957-80-8Relevant articles and documents
PYRIMIDINE FGFR4 INHIBITORS
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Page/Page column 39, (2015/05/05)
Provided herein are compounds of Formula I useful as FGFR4 inhibitors, as well as methods of use of the same.
