1219980-35-4Relevant academic research and scientific papers
Compounds with cardiac myosin activating function and pharmaceutical composition containing the same for treating or preventing heart failure
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Paragraph 0613-0616, (2016/10/07)
Disclosed are a compound having cardiotonic activity and a pharmaceutical composition containing the same, and the composition containing the compound, according to the present invention, is useful for preventing and treating heart failure.COPYRIGHT KIPO 2016
Inhibitory effect of novel tetrahydropyrimidine-2(1H)-thiones on melanogenesis
Thanigaimalai,Lee, Ki-Cheul,Bang, Seong-Cheol,Lee, Jee-Hyun,Yun, Cheong-Yong,Roh, Eunmiri,Hwang, Bang-Yeon,Kim, Youngsoo,Jung, Sang-Hun
experimental part, p. 1135 - 1142 (2010/04/24)
The series of imidazoldine-2-thiones 2 and tetrahydropyrimidine-2-thiones 3 were discovered as inhibitor of α-MSH-induced melanin production in melanoma B16 cells. The primary bioassay showed that 1-(4-ethylbenzyl)-tetrahydropyrimidine-2(1H)-thione 3e (>1
