122005-12-3Relevant academic research and scientific papers
Synthesis of cicerfuran, an antifungal benzofuran, and some related analogues
Aslam, Shazia N.,Stevenson, Philip C.,Phythian, Sara J.,Veitch, Nigel C.,Hall, David R.
, p. 4214 - 4226 (2007/10/03)
Routes were investigated for the synthesis of cicerfuran, a hydroxylated benzofuran from wild chickpea implicated in resistance to Fusarium wilt, and some of its analogues. A novel method is described for the synthesis of oxygenated benzofurans by epoxidation and cyclisation of 2′-hydroxystilbenes. The stilbene intermediates required could be synthesised by palladium-catalysed coupling of styrenes with mono-oxygenated aryl halides but not with di-oxygenated aryl halides. Stilbenes corresponding to the latter were synthesised by Wittig reactions.
Syntheses of Flavonoids via the Isoxazoline Route
Almtorp, Gunvor T.,Bachmann, Torben L.,Torsell, Kurt B. G.
, p. 212 - 215 (2007/10/02)
Syntheses of naturally occuring 7-hydroxyflavonone, liquiritigenin and the corresponding chalcones (isoliquiritigenin) are described.
