1220095-03-3Relevant academic research and scientific papers
Azabicyclic sulfonamides as potent 11β-HSD1 inhibitors
Shah, Unmesh,Boyle, Craig D.,Chackalamannil, Samuel,Baker, Hana,Kowalski, Timothy,Lee, Julie,Terracina, Giuseppe,Zhang, Lili
, p. 1551 - 1554 (2010)
Inhibition of 11β-HSD1 has demonstrated potential in the treatment of various components of metabolic syndrome. We wish to report herein the discovery of novel azabicyclic sulfonamide based 11β-HSD1 inhibitors. Highly potent compounds exhibiting inhibitor
