1220101-68-7Relevant academic research and scientific papers
Novel multiple opioid ligands based on 4-aminobenzazepinone (Aba), azepinoindole (Aia) and tetrahydroisoquinoline (Tic) scaffolds
Ballet, Steven,Marczak, Ewa D.,Feytens, Debby,Salvadori, Severo,Sasaki, Yusuke,Abell, Andrew D.,Lazarus, Lawrence H.,Balboni, Gianfranco,Tourwé, Dirk
, p. 1610 - 1613 (2010)
The dimerization and trimerization of the Dmt-Tic, Dmt-Aia and Dmt-Aba pharmacophores provided multiple ligands which were evaluated in vitro for opioid receptor binding and functional activity. Whereas the Tic- and Aba multimers proved to be dual and bal
