1220105-02-1Relevant academic research and scientific papers
Sequential perfluoroalkylation and asymmetric reduction of nitriles triggered with perfluoroalkyl titanates: catalytic asymmetric synthesis of perfluoroalkyl amines
Mikami, Koichi,Murase, Tatsushi,Zhai, Lili,Kawauchi, Susumu,Itoh, Yoshimitsu,Ito, Shigekazu
scheme or table, p. 1371 - 1373 (2010/05/19)
Highly enantio-enriched perfluoroalkyl amines are shown to be synthesized by perfluoroalkylation and asymmetric reduction of nitriles. Perfluoroalkylation of nitriles can be attained by the Lewis acidic perfluoroalkyl titanate reagents to give acyclic ket
Highly enantioselective synthesis of α-(perfluoroalkyl)amines via hydrogenation of enamide precursors in the presence of chiraphos-rhodium catalyst
Mikami, Koichi,Murase, Tatsushi,Zhai, Lili,Itoh, Yoshimitsu,Ito, Shigekazu
scheme or table, p. 1158 - 1161 (2010/10/20)
Highly (up to 99% ee) enantio-enriched perfluoroalkyl amines can be synthesized by the perfluoroalkylation of nitriles with Lewis acidic perfluoroalkyl titanate reagents and catalytic asymmetric hydrogenation with the chiraphos-Rh catalyst of the resultan
