1220282-58-5Relevant academic research and scientific papers
Synthesis of Substituted Acridines through a Palladium-Catalyzed Condensation/Cyclization/Tautomerization Sequence
Chen, Xiangui,Xie, Yanjun,Li, Cheng,Xiao, Fuhong,Deng, Guo-Jun
, p. 577 - 581 (2017)
Herein, we report an efficient strategy for the synthesis of 9-aryl-substituted acridines from cyclohexanones and 2-aminobenzophenones in the presence of a palladium catalyst. Molecular oxygen is applied as a green oxidant. Various cyclohexanones acted as the aryl source to construct the nitrogen-containing heterocycles through a condensation/cyclization/tautomerization sequence.
Synthesis of acridines by the [4 + 2] annulation of arynes and 2-aminoaryl ketones
Rogness, Donald C.,Larock, Richard C.
supporting information; experimental part, p. 2289 - 2295 (2010/07/02)
(Figure Presented) The reaction of 2-aminoaryl ketones and arynes generated by the treatment of various o-(trimethylsilyl)aryl triflates with CsF results in [4 + 2] annulation to afford substituted acridines in good yields.
