1220351-60-9

Basic information

• Product Name: 6-chloro-2-(4-methoxyphenyl)-3-(4-nitrophenyl)imidazo[1,2-b]pyridazine
• Synonyms: 6-chloro-2-(4-methoxyphenyl)-3-(4-nitrophenyl)imidazo[1,2-b]pyridazine
• CAS NO: 1220351-60-9
• Molecular Weight: 380.79
• Mol File: 1220351-60-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-chloro-2-(4-methoxyphenyl)-3-(4-nitrophenyl)imidazo[1,2-b]pyridazine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-2-(4-methoxyphenyl)-3-(4-nitrophenyl)imidazo[1,2-b]pyridazine(1220351-60-9)
• EPA Substance Registry System: 6-chloro-2-(4-methoxyphenyl)-3-(4-nitrophenyl)imidazo[1,2-b]pyridazine(1220351-60-9)

Safety Data

• Hazardous Substances Data: 1220351-60-9(Hazardous Substances Data)

Upstream product

• 1844-55-9 6-chloro-2-(4-methoxy-phenyl)-imidazo[1,2-b]pyridazine 
• 586-78-7 para-nitrophenyl bromide 

Relevant articles and documents

Direct arylation of Imidazo[l,2-b]pyridazines: microwave-assisted one-pot Suzuki coupling/Pd-catalysed arylation

Direct intermolecular C-H arylation of 6-chloroimidazo [ 1,2 - b] pyridazine in its 3-position was achieved, and the tolerance to reaction conditions in the presence of chloro groups was investigated. Various 3-(hetero)arylimidazo[l,2-b]pyridazines were synthesized in good to excellent yields. This methodology was successfully applied to the synthesis of 3,6-diand 2,3,6-trisubstituted imidazo[l,2-5]pyridazines by a microwave-assisted, one-pot, two-step Suzuki cross-coupling/ palladium-catalysed arylation process.