1220392-72-2Relevant academic research and scientific papers
Ipso -Iodocyclization of ethoxyethyl ethers to alkynes at the ortho -position: An efficient synthesis of functionalized spiro compounds
Okitsu, Takashi,Nakazawa, Daisuke,Kobayashi, Akihiro,Mizohata, Masahiro,In, Yasuko,Ishida, Toshimasa,Wada, Akimori
, p. 203 - 206 (2010)
An efficient approach to the synthesis of azaspiro compounds having dissymmetric dienone cores was achieved by ipso-iodocyclization of ethoxyethyl ether to alkynes. When the linker was an ether or an ester, domino iodocyclizaion/Diels-Alder reaction proceeded to afford the dimer, which can be transformed into the bridgehead-spiro connection ring system by a domino retro-Diels-Alder/Diels-Alder process.
