122040-07-7

Upstream product

• 22465-60-7 methyl abieta-8,11,13,15-tetraen-18-oate 
• 122040-02-2 methyl (15R)-12-acetoxy-16-benzoyloxy-8,11,13-abietatrien-18-oate 
• 122040-01-1 methyl (15R)-12-acetyl-16-benzoyloxy-8,11,13-abietatrien-18-oate 
• 122040-05-5 methyl (16R)-16-benzoyloxy-12-hydroxy-8,11,13-abietatrien-18-oate 
• 122039-83-2 methyl 6-hydroxy-8,11,13,15-abietatrien-18-oate 
• 14210-25-4 5-Chloro-1-phenyltetrazole 
• 122040-06-6 methyl (15R)-16-benzoyloxy-12-(1-phenyl-1H-tetrazol-5-yloxy)-8,11,13-abietatrien-18-oate 

Relevant academic research and scientific papers

The Synthesis of Methyl (15S)-16-Hydroxydehydroabietate and Its (15R)-Epimer

In order to elucidate the absolute configuration of C-15 in natural 16-hydroxydehyroabietic acid, a metabolite of (+)-dehydroabietic acid in rabbits, methyl (+)-dehydroabietate was transformed into methyl (15S)-16-hydroxy-8,11,13-abietatrien-18-oate (3a) and its (15R)-epimer (3b).The synthetic 3a was identical with a methyl ester derived from the natural acid.Thus, the absolute configuration of C-15 in natural 16-hydroxydehydroabietic acid was conclusively assigned as an S-configuration.