1220449-49-9

Upstream product

• 1220449-34-2 4-[N-(6-chloro-5-nitropyrimidin-4-yl)amino]benzenesulfonamide 
• 503309-11-3 2-fluoro-4-(trifluoromethyl)phenylboronic acid 

Downstream Products

• 1220449-51-3 4-[5-amino-6-(2-fluoro-4-trifluoromethyl-phenyl)-pyrimidin-4-ylamino]-benzenesulfonamide 

Relevant academic research and scientific papers

6-PHENYL-PYRIMIDIN-4-YL-(PHENYLAMINE OR PHENOXY) DERIVATIVES USEFUL AS MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS

This invention relates to novel 6-phenyl-pyhmidin-4-yl-(phenylannine or phenoxy) derivatives, which are found to be modulators of the nicotinic acetylcholine receptors. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.

NOVEL DIPHENYL PURINE DERIVATIVES USEFUL AS MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS

This invention relates to novel (6-phenyl-5-amino/nitro-pyrimidin-4-yl)- phenyl-amines, which are found to be modulators of the nicotinic acetylcholine receptors. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.