1220630-83-0

Basic information

• Product Name: 3-Amino-4-(trifluoromethyl)benzonitrile
• Synonyms: 3-Amino-4-(trifluoromethyl)benzonitrile;2-Amino-4-cyanobenzotrifluoride, 5-Cyano-alpha,alpha,alpha-trifluoro-o-toluidine;3-Amino-4-(trifluoromethyl)
• CAS NO: 1220630-83-0
• Molecular Formula: C₈H₅F₃N₂
• Molecular Weight: 186.1339096
• Mol File: 1220630-83-0.mol

Chemical Properties

• Boiling Point: 286.6±40.0 °C(Predicted)
• Appearance: /
• Density: 1.37±0.1 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: -0.35±0.10(Predicted)
• CAS DataBase Reference: 3-Amino-4-(trifluoromethyl)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Amino-4-(trifluoromethyl)benzonitrile(1220630-83-0)
• EPA Substance Registry System: 3-Amino-4-(trifluoromethyl)benzonitrile(1220630-83-0)

Safety Data

• Hazardous Substances Data: 1220630-83-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3-Amino-4-(trifluoromethyl)benzonitrile is used as an intermediate in the synthesis of various pharmaceuticals for its potent biological activity, contributing to the development of new drugs with improved therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, 3-Amino-4-(trifluoromethyl)benzonitrile is employed as a building block in the creation of effective agrochemicals, enhancing crop protection and yield.
Used in Dye and Pigment Production:
3-Amino-4-(trifluoromethyl)benzonitrile is utilized in the production of dyes and pigments, offering a wide range of color options and properties for various applications, including textiles, plastics, and inks.
Used in Organic Compound Synthesis:
This chemical compound is also used as a versatile intermediate in the synthesis of other organic compounds, expanding its applications in research and development across multiple industries.

Upstream product

• 1220630-84-1 3-(4-methoxybenzylamino)-4-(trifluoromethyl)benzonitrile 
• 231953-38-1 3-fluoro-4-(trifluoromethyl)benzonitrile 

Downstream Products

• 1242269-76-6 tert-butyl N-[5-(aminomethyl)-2-(trifluoromethyl)phenyl]carbamate 
• 1380921-40-3 3-isothiocyanato-4-trifluoromethyl-benzonitrile 
• 1242269-75-5 tert-butyl N-[5-cyano-2-(trifluoromethyl)phenyl]carbamate 

Relevant articles and documents

2 -AMINOBENZ IMIDAZOLE DERIVATIVES USEFUL IN THE TREATMENT OF INFLAMMATION

This invention relates to compounds of formula (I), their use as inhibitors of the microsomal prostaglandin E2 synthase-1 (mPGES-1), pharmaceutical compositions containing them, and their use as medicaments for the 10 treatment and/or prevention of inflammatory diseases and associated conditions. A, M, W, R1, R2, R3, R4, R6, R2,R7, R8, R9, Ra, Rb have meanings given in the description.

NOVEL COMPOUNDS

This invention relates to compounds of formula I their use as inhibitors of the microsomal prostaglandin E2 synthase-1 (mPGES-1), to pharmaceutical compositions containing them, and their use as medicaments for the treatment and/or prevention of inflammatory diseases and associated conditions. A, M, W, R1, R2, R3, R4, R6, R2, R7, R8, R9, Ra, Rb have meanings given in the description.

3H-IMIDAZO [4, 5 -C] PYRIDINE- 6 -CARBOXAMIDES AS ANTI- INFLAMMATORY AGENTS

The present invention relates to compounds of general formula (I) in which A, L, M, Q2, Q3, Q4, R1, R5, Ra, Rb, Rc, W, X, Y, Z1, Z2, Z3 are defined in the description, the salts thereof, particularly the physiologically acceptable salts thereof. The compounds are of potential utility in the treatment and/or prevention of inflammatory diseases and associated conditions, in particular, in the treatment and/or prevention of pain. The invention also relates to the use of such compounds as medicaments, to pharmaceutical compositions containing them, and to their preparation.

IMIDAZOPYRIDAZINECARBONITRILES USEFUL AS KINASE INHIBITORS

The invention provides compounds of Formula (I) and pharmaceutically acceptable salts thereof. The Formula (I) imidazopyridazines inhibit protein kinase activity thereby making them useful as anticancer agents.