1220699-06-8 Usage
General Description
PF-04979064 is a selective and potent inhibitor of the 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) enzyme, which is involved in regulating the levels of cortisol in the body. Inhibition of this enzyme can potentially have therapeutic effects in conditions such as type 2 diabetes, metabolic syndrome, and obesity. PF-04979064 has shown promising results in preclinical studies, demonstrating its ability to lower cortisol levels and improve glucose metabolism. It is currently being investigated for its potential as a treatment for metabolic disorders, with the aim of improving insulin sensitivity and reducing the risk of cardiovascular disease. Additionally, PF-04979064 may have potential applications in the treatment of inflammatory and immune-related diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 1220699-06-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,0,6,9 and 9 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1220699-06:
(9*1)+(8*2)+(7*2)+(6*0)+(5*6)+(4*9)+(3*9)+(2*0)+(1*6)=138
138 % 10 = 8
So 1220699-06-8 is a valid CAS Registry Number.
1220699-06-8Relevant articles and documents
IMIDAZO[1,5]NAPHTHYRIDINE COMPOUNDS, THEIR PHARMACEUTICAL USE AND COMPOSITIONS
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Page/Page column 103, (2010/04/27)
The present invention is directed to compounds of Formula (I), and to salts thereof, their synthesis, and their use as PI3-Kalpha inhibitors and/or PI3- Kalpha/mTOR dual inhibitors
