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CAS

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1220701-14-3

2-(methylthio)-4-(2-(3-nitrophenyl)-1H-imidazol-1-yl)pyrimidine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1220701-14-3 Structure

  • Basic information

    1. Product Name: 2-(methylthio)-4-(2-(3-nitrophenyl)-1H-imidazol-1-yl)pyrimidine
    2. Synonyms: 2-(methylthio)-4-(2-(3-nitrophenyl)-1H-imidazol-1-yl)pyrimidine
    3. CAS NO:1220701-14-3
    4. Molecular Formula:
    5. Molecular Weight: 313.34
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1220701-14-3.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-(methylthio)-4-(2-(3-nitrophenyl)-1H-imidazol-1-yl)pyrimidine(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-(methylthio)-4-(2-(3-nitrophenyl)-1H-imidazol-1-yl)pyrimidine(1220701-14-3)
    11. EPA Substance Registry System: 2-(methylthio)-4-(2-(3-nitrophenyl)-1H-imidazol-1-yl)pyrimidine(1220701-14-3)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1220701-14-3(Hazardous Substances Data)

1220701-14-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1220701-14-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,0,7,0 and 1 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1220701-14:
(9*1)+(8*2)+(7*2)+(6*0)+(5*7)+(4*0)+(3*1)+(2*1)+(1*4)=83
83 % 10 = 3
So 1220701-14-3 is a valid CAS Registry Number.

1220701-14-3Relevant articles and documents

IMIDAZOLE DERIVATIVES AND COMPOSITIONS FOR TREATING MELANOMA

-

, (2011/05/06)

The present invention relates to novel imidazole derivatives or pharmaceutically acceptable salts thereof, preparation methods thereof and pharmaceutical compositions for prevention and treatment of melanoma containing the same as active ingredients. The

Discovery and initial SAR of pyrimidin-4-yl-1H-imidazole derivatives with antiproliferative activity against melanoma cell lines

Lee, Junghun,Kim, Hwan,Yu, Hana,Chung, Jae Yoon,Oh, Chang-Hyun,Yoo, Kyung Ho,Sim, Taebo,Hah, Jung-Mi

scheme or table, p. 1573 - 1577 (2010/06/20)

The synthesis of a novel series of pyrimidin-4-yl-1H-imidazol-2-yl derivatives 7, 8, 9 and their antiproliferative activities against A375P human melanoma cell line and WM3629 cell line were described. Most compounds showed superior antiproliferative activities compared to Sorafenib, the well-known RAF inhibitor. Among them, 7a exhibited potent activities on both cell lines (IC50 = 0.62 and 4.49 μM, respectively) and turned out to be a selective and potent CRAF inhibitor.

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