1220892-85-2

Downstream Products

• 1220892-50-1 N-(4-chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylaminoformoxyl)-4-(7-aminoisoquinolyl)oxy)phenyl)urea 
• 1220892-51-2 N-(4-fluoro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylaminoformoxyl)-4-(7-aminoisoquinolyl)oxy)phenyl)urea 
• 1220892-52-3 N-(4-bromo-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylaminoformoxyl)-4-(7-aminoisoquinolyl)oxy)phenyl)urea 

Relevant academic research and scientific papers

Heterocyclic Substituted Acardite Derivate and Application Thereof

This present invention discloses a heterocyclic substituted acardite derivate and application thereof, namely compounds in the general formula (1) or the general formula (2) or pharmaceutically acceptable salts thereof, wherein A is monosubstituted or polysubstituted quinoline, isoquinoline, quinazoline, pyrrole or pyrimidine, and the substituent is halogen, C1-5alkyl, C1-5haloalkyl, C1-5alkoxy, C1-5haloalkoxy, C1-5alkylamino, C1-5haloalkylamino, amino or nitryl; R1 is C1-5alkyl; R2 is one or more selected from hydrogen, halogen, alkyl, alkoxy, haloalkyl or haloalkoxy; and R3 is one or more selected from hydrogen, halogen, alkyl, alkoxy, haloalkyl or haloalkoxy. The compound of the present invention and the pharmaceutically acceptable salt thereof can be used for treating tumor or leukemia.

HETEROCYCLIC SUBSTITUTED ACARDITE DERIVATES AND USE THEREOF

The present invention discloses a heterocyclic substituted acardite derivate and application thereof, namely compounds of the general formula (1) or the general formula (2) or pharmaceutically acceptable salts thereof, wherein A is monosubstituted or polysubstituted quinoline, isoquinoline, quinazoline, pyrrole or pyrimidine, and the substituent is halogen, C1-5alkyl, C1-5haloalkyl, C1-5alkoxy, C1-5haloalkoxy, C1-5alkylamino, C1-5haloalkylamino, amino or nitryl; R1 is C1-5alkyl; R2 is one or more selected from hydrogen, halogen, alkyl, alkoxy, haloalkyl or haloalkoxy; and R3 is one or more selected from hydrogen, halogen, alkyl, alkoxy, haloalkyl or haloalkoxy. The compound of the present invention and the pharmaceutically acceptable salt thereof can be used for treating tumor or leukemia.