1220909-56-7

Basic information

• Product Name: C₁₄H₁₃FN₄
• CAS NO: 1220909-56-7
• Molecular Weight: 256.282
• Mol File: 1220909-56-7.mol

Chemical Properties

• CAS DataBase Reference: C₁₄H₁₃FN₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₄H₁₃FN₄(1220909-56-7)
• EPA Substance Registry System: C₁₄H₁₃FN₄(1220909-56-7)

Safety Data

• Hazardous Substances Data: 1220909-56-7(Hazardous Substances Data)

Upstream product

• 37904-72-6 2-bromo-1-(4-(dimethylamino)phenyl)ethanone 
• 108784-42-5 6-fluoro-pyridazin-3-yl amine 

Relevant articles and documents

Synthesis and in vitro evaluation of imidazo[1,2- b ]pyridazines as ligands for β-amyloid plaques

A series of imidazo[1,2-b]pyridazine derivatives were synthesized and evaluated for binding to amyloid plaques in vitro using synthetic aggregates of Aβ1?40. Binding affinities of these compounds were found to range from 11.0 to >1000 nM, depending on the various substitution patterns in the 6-position and 2-position. 2-(4′-Dimethylaminophenyl)-6- (methylthio)imidazo[1,2-b]pyridazine (4) showed high binding affinity (K i = 11.0 nM) and might be useful for the development of novel positron emission tomography radiotracers for imaging Aβ plaques.