1220968-24-0

Basic information

• Product Name: Ethyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanoate
• Synonyms: Ethyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanoate
• CAS NO: 1220968-24-0
• Molecular Formula: C₁₄H₂₃BN₂O₄
• Molecular Weight: 294.15442
• Mol File: 1220968-24-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 394.1±22.0 °C(Predicted)
• Appearance: /
• Density: 1.11±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• PKA: 1.51±0.10(Predicted)
• CAS DataBase Reference: Ethyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanoate(1220968-24-0)
• EPA Substance Registry System: Ethyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanoate(1220968-24-0)

Safety Data

• Hazardous Substances Data: 1220968-24-0(Hazardous Substances Data)

Usage

General Description

Ethyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanoate is a chemical compound used in the field of organic synthesis. It contains a pyrazole ring and a boron-containing group, making it useful in the development of pharmaceuticals, agrochemicals, and materials science. The ethyl ester group also makes it a potential precursor for the synthesis of various other organic compounds. This chemical has potential applications in the development of new drugs and materials due to its unique structure and reactivity.

Upstream product

• 51292-41-2 ethyl 2-(4-bromo-1H-pyrazol-1-yl)propanoate 
• 73183-34-3 bis(pinacol)diborane 
• 535-11-5 Ethyl 2-bromopropionate 
• 269410-08-4 pyrazole-4-boronic acid pinacol ester 

Downstream Products

• 1383480-46-3 N-cyclopropyl-2-(4-{3-[3-({[(2,2,2-trifluoroethyl)amino]carbonyl}amino)phenyl]imidazo[1,2-b]pyridazin-7-yl}-1H-pyrazol-1-yl)propanamide 
• 1383481-19-3 2-(4-{3-[3-({[(2,2,2-trifluoroethyl)amino]carbonyl}amino)phenyl]imidazo[1,2-b]pyridazin-7-yl}-1H-pyrazol-1-yl)propanoic acid 

Relevant articles and documents

DGAT1 INHIBITOR AND PREPARATION METHOD AND USE THEREOF

The present invention discloses a novel DGAT1 inhibitor, especially the compound of formula (I) or a pharmaceutically acceptable salt thereof, preparation and pharmaceutical composition thereof, as well as their uses in the preparation of a medicament for the prevention and treatment of Familial hyperchylomicronemia (FCS), obesity, hyperlipoproteinemia or hypertriglyceridemia.

SUBSTITUTED IMIDAZOPYRIDAZINES AND BENZIMIDAZOLES AS INHIBITORS OF FGFR3

The present invention relates to substituted imidazopyridazines and substituted benzimidazoles, as well as pharmaceutical compositions comprising the same, which are FGFR3 inhibitors useful in the treatment of cancer and other diseases.