1220973-37-4 Usage
General Description
AKP-11 is a highly potent and selective inhibitor of bromodomain and extra-terminal domain (BET) proteins, which play a critical role in gene regulation. This small molecule has been shown to effectively inhibit the binding of BET proteins with chromatin, leading to the suppression of key oncogenes and proliferation-related genes. AKP-11 exhibits anti-proliferative and anti-inflammatory properties, making it a promising candidate for the treatment of various cancers and inflammatory diseases. Furthermore, AKP-11 has demonstrated good pharmacokinetic properties and is well-tolerated in preclinical studies, highlighting its potential as a therapeutic agent for a range of diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 1220973-37-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,0,9,7 and 3 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1220973-37:
(9*1)+(8*2)+(7*2)+(6*0)+(5*9)+(4*7)+(3*3)+(2*3)+(1*7)=134
134 % 10 = 4
So 1220973-37-4 is a valid CAS Registry Number.
1220973-37-4Relevant articles and documents
ORGANIC COMPOUNDS
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, (2014/05/24)
Novel benzofuran derivatives are disclosed. The derivatives have S1P1 receptor activity and/or disease modifying activity and find use in the treatment of conditions or diseases associated with the immune, vascular and nervous systems in animals and/or humans
