1220995-75-4Relevant academic research and scientific papers
Simultaneous functionalization and cyclization of 2-ethynylaniline derivatives to indoles
Hiroya, Kou,Itoh, Shin,Inamoto, Kiyofumi,Shigehisa, Hiroki,Sakamoto, Takao
, p. 920 - 933 (2017/07/27)
Two different kind of sequential cyclization-functionalization are developed. Namely, cyclization-chlorination of 2-ethynylaniline derivatives using CuCl2 gave 3-chloro- and 3,5-dichloroindole derivatives. The plausible mechanism for this react
Cupric halide-mediated intramolecular halocyclization of N-electron-withdrawing group-substituted 2-alkynylanilines for the synthesis of 3-haloindoles
Shen, Zengming,Lu, Xiyan
scheme or table, p. 3107 - 3112 (2010/04/28)
A convenient and efficient method for the synthesis of 3-haloindoles has been developed. Both 3-chloro-and 3-bromoindole derivatives can be obtained in high yields by the reaction of N-electron-withdrawing group-substituted 2-alkynylanilines with cupric h
