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5-amino-3-(4-bromophenyl)-N-isopropyl-4-oxo-3,4-dihydrothieno[3,4-d]pyridazine-1-carboxamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1221069-65-3

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1221069-65-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1221069-65-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,1,0,6 and 9 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1221069-65:
(9*1)+(8*2)+(7*2)+(6*1)+(5*0)+(4*6)+(3*9)+(2*6)+(1*5)=113
113 % 10 = 3
So 1221069-65-3 is a valid CAS Registry Number.

1221069-65-3Downstream Products

1221069-65-3Relevant academic research and scientific papers

AMINOTHIENOPYRIDAZINE INHIBITORS OF TAU ASSEMBLY

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Page/Page column 33, (2011/04/24)

The present invention is directed to methods of inhibiting a tauopathy in a patient by administration of a compound of formula (I): Novel aminothienopyridazine compounds are also described.

Discovery of brain-penetrant, orally bioavailable aminothienopyridazine inhibitors of Tau aggregation

Ballatore, Carlo,Brunden, Kurt R.,Piscitelli, Francesco,James, Michael J.,Crowe, Alex,Yao, Yuemang,Hyde, Edward,Trojanowski, John Q.,Lee, Virginia M.-Y.,Smith, Amos B.

experimental part, p. 3739 - 3747 (2010/08/06)

Agents capable of preventing the misfolding and sequestration of the microtubule-stabilizing protein tau into insoluble fibrillar aggregates hold considerable promise for the prevention and/or treatment of neurodegenerative tauopathies such as Alzheimer's

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