122116-46-5

Upstream product

• 26922-15-6 benzyl 3-O-benzyl-2-(benzyloxycarbonyl)amino-2-deoxy-α-D-glucopyranoside 
• 339317-37-2 ((2S,3R,4R,5S,6R)-2,4-Bis-benzyloxy-5-hydroxy-6-hydroxymethyl-tetrahydro-pyran-3-yl)-carbamic acid 2,2,2-trichloro-ethyl ester 

Downstream Products

• 122116-47-6 Benzyl-2-acetamido-4,6-di-O-acetyl-3-O-benzyl-2-desoxy-α-D-glucopyranosid 
• 122116-54-5 Benzyl-4-O-acetyl-6-O-<3,4,6-tri-O-acetyl-<(R)-3-benzyloxytetradecanoylamino>-2-desoxy-β-D-glucopyranosyl>-3-O-benzyl-2-<(R)-3-benzyloxytetradecanoylamino>-2-desoxy-α-D-glucopyranosid 
• 122116-56-7 Benzyl-3-O-benzyl-2-<(R)-3-benzyloxytetradecanoylamino>-6-O-<2-<(R)-3-benzyloxytetradecanoylamino>-2-desoxy-4,6-O-tetraisopropyldisiloxan-1,3-diyl-β-D-glucopyranosyl>-2-desoxy-α-D-glucopyranosid 
• 122116-51-2 Benzyl-4-O-acetyl-6-O-<3,4,6-tri-O-acetyl-2-desoxy-2-(2,2,2-trichlorethoxycarbonylamino)-β-D-glucopyranosyl>-3-O-benzyl-2-<(R)-3-benzyloxytetradecanoylamino>-2-desoxy-α-D-glucopyranosid 
• 122116-50-1 Benzyl-6-O-<3,4,6-tri-O-acetyl-2-desoxy-2-(2,2,2-trichlorethoxycarbonylamino)-β-D-glucopyranosyl>-3-O-benzyl-2-<(R)-3-benzyloxytetradecanoylamino>-2-desoxy-α-D-glucopyranosid 
• 122116-55-6 Benzyl-3-O-benzyl-2-<(R)-3-benzyloxytetradecanoylamino>-6-O-<2-<(R)-3-benzyloxytetradecanoylamino>-2-desoxy-β-D-glucopyranosyl>-2-desoxy-α-D-glucopyranosid 
• 122116-53-4 Benzyl-6-O-(2-acetamido-3,4,6-tri-O-acetyl-2-desoxy-β-D-glucopyranosyl)-4-O-acetyl-3-O-benzyl-2-<(R)-3-benzyloxytetradecanoylamino>-2-desoxy-α-D-glucopyranosid 
• 122116-52-3 Benzyl-4-O-acetyl-6-O-(3,4,6-tri-O-acetyl-2-amino-2-desoxy-β-D-glucopyranosyl)-3-O-benzyl-2-<(R)-3-benzyloxytetradecanoylamino>-2-desoxy-α-D-glucopyranosid 
• 122116-49-8 Benzyl-4,6-di-O-acetyl-3-O-benzyl-2-<(R)-3-benzyloxytetradecanoylamino>-2-desoxy-α-D-glucopyranosid 
• 122116-48-7 Benzyl-3-O-benzyl-2-<(R)-3-benzyloxytetradecanoylamino>-2-desoxy-α-D-glucopyranosid 

Relevant academic research and scientific papers

Lipid A structures containing novel lipid moieties: Synthesis and adjuvant properties

Structurally well-defined immune stimulatory molecules are important components of new generation molecular vaccines. In this paper, the design and synthesis of two lipid A analogues containing an unnatural tri-lipid acyl group are described. In a totally synthetic liposomal vaccine system, these re-designed lipid A analogues demonstrate potent immune stimulatory properties including antigen specific T-cell activation.

Building Units of Oligosaccharides, XCIV. - Synthesis of KDO-Containing Tri- and Tetrasaccharide Sequences of the Inner Core and Lipoid A Region of Lipopolysaccharides

The glycosyl acceptor 18, who contains two glycosidically β(1->6) linked 2-amino-2-deoxy-D-glucose residues was synthesized.The two amino groups are acetylated with (R)-3-hydroxytetradecanoic acid.The 6' position of 18 is suitable for selective glycosidat