1221172-11-7 Usage
General Description
6-(trifluoromethoxy)picolinic acid is a chemical compound with the molecular formula C8H5F3NO3. It is a derivative of picolinic acid, a heterocyclic compound containing a pyridine ring structure. The introduction of a trifluoromethoxy group to the picolinic acid molecule enhances its lipophilicity and can potentially improve its bioavailability and pharmacokinetic properties. 6-(trifluoromethoxy)picolinic acid has been studied for its potential applications in the development of pharmaceuticals and agrochemicals due to its unique chemical structure and properties. Additionally, its fluorinated nature may offer advantages in terms of metabolic stability and binding affinity to biological targets, making it a promising building block for the synthesis of novel drug candidates.
Check Digit Verification of cas no
The CAS Registry Mumber 1221172-11-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,1,1,7 and 2 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1221172-11:
(9*1)+(8*2)+(7*2)+(6*1)+(5*1)+(4*7)+(3*2)+(2*1)+(1*1)=87
87 % 10 = 7
So 1221172-11-7 is a valid CAS Registry Number.
1221172-11-7Relevant articles and documents
IRAK DEGRADERS AND USES THEREOF
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, (2021/01/23)
The present invention provides compounds, compositions thereof, and methods of using the same. The compounds include an IRAK binding moiety capable of binding to IRAK4 and a degradation inducing moiety (DIM). The DIM could be DTM a ligase binding moiety (LBM) or lysine mimetic. The compounds could be useful as IRAK protein kinase inhibitors and applied to IRAK mediated disorders.
METHOD FOR THE PREPARATION OF FUNCTIONALIZED TRIHALOMETHOXY SUBSTITUTED PYRIDINES
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Page/Page column 51, (2010/04/28)
The present invention pertains to a process for the preparation of functionalized trihalomethoxypyridines of formula (I) comprising reacting hydroxypyridines with thiophosgene in the presence of a base; reacting the obtained chlorothionoformiates with elemental chlorine and finally converting trichloromethoxy pyridines to trihalomethoxy pyridines using a fluoride source.
