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1221185-59-6

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1221185-59-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1221185-59-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,1,1,8 and 5 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1221185-59:
(9*1)+(8*2)+(7*2)+(6*1)+(5*1)+(4*8)+(3*5)+(2*5)+(1*9)=116
116 % 10 = 6
So 1221185-59-6 is a valid CAS Registry Number.

1221185-59-6Relevant articles and documents

Substituted thieno[2,3-d]pyrimidines as adenosine A2A receptor antagonists

Shook, Brian C.,Chakravarty, Devraj,Barbay, J. Kent,Wang, Aihua,Leonard, Kristi,Alford, Vernon,Powell, Mark T.,Rassnick, Stefanie,Scannevin, Robert H.,Carroll, Karen,Wallace, Nathaniel,Crooke, Jeffrey,Ault, Mark,Lampron, Lisa,Westover, Lori,Rhodes, Kenneth,Jackson, Paul F.

, p. 2688 - 2691 (2013/06/27)

A novel series of benzyl substituted thieno[2,3-d]pyrimidines were identified as potent A2A receptor antagonists. Several five- and six-membered heterocyclic replacements for the optimized methylfuran were explored. Select compounds effectively reverse catalepsy in mice when dosed orally.

PHENYL SUBSTITUTED THIENO [2,3-D] PYRIMIDINES AND THEIR USE AS ADENOSINE A2A RECEPTOR ANTAGONISTS

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Page/Page column 25, (2010/04/30)

This invention relates to a novel thieno[2,3-d]pyrimidine, Z, and its therapeutic and prophylactic uses, wherein R1 and R2 are definedin the specification. Disorders treated and/or prevented include Parkinson's Disease.

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