1221254-27-8

Basic information

• Product Name: C₃₅H₅₉F₃NO₂
• CAS NO: 1221254-27-8
• Molecular Weight: 582.854
• Mol File: 1221254-27-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₅H₅₉F₃NO₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₅H₅₉F₃NO₂(1221254-27-8)
• EPA Substance Registry System: C₃₅H₅₉F₃NO₂(1221254-27-8)

Safety Data

• Hazardous Substances Data: 1221254-27-8(Hazardous Substances Data)

Upstream product

• 24973-59-9 2,4,6-tri-tert-butyl-1-nitrosobenzene 
• 141022-99-3 1,1,1-trifluoro-2-heptadecanone 

Relevant articles and documents

EPR/Spin-trapping study of free radical intermediates in the photolysis of trifluoromethyl ketones with initiators

Photolysis of trifluoromethyl ketones (TFMKs) 1a-1e versus the non-fluorinated ketones 2a-2b in the presence of radical initiators by electron paramagnetic resonance spectroscopy has been studied for the first time. The transient radicals generated after irradiation of the ketones were identified by trapping with 2-methyl-2-nitrosopropane (MNP) and 2,4,6-tritert- butylnitrosobenzene (TTBNB) as spin traps. TTBNB is a powerful, particularly useful spin trap in these kinds of processes producing anilino and nitroxyl spin adducts due to the ambivalent reactivity on the N and O atoms. In the presence of t-butylperoxide, short-chain TFMKs, such as 1,1,1-trifluoroacetone (1d) and hexafluoroacetone (1e), give rise to detection of the elusive trifluoromethyl radical. In contrast, long-chain TFMKs did not provide clues to prove formation of the trifluoromethyl radical but instead to radicals derived by abstraction of one α-methylene proton to the carbonyl. Although TFMKs are quite stable to photodegradation in the absence of initiator, methyl ketone 2b and phenyl ketone 3 produce radicals resulting from abstraction of a γ-hydrogen to the carbonyl group. Copyright