1221292-97-2Relevant academic research and scientific papers
Novel pyrazolo-tetrahydropyridines as potent orexin receptor antagonists
Sifferlen, Thierry,Boss, Christoph,Cottreel, Emmanuelle,Koberstein, Ralf,Gude, Markus,Aissaoui, Hamed,Weller, Thomas,Gatfield, John,Brisbare-Roch, Catherine,Jenck, Francois
scheme or table, p. 1539 - 1542 (2010/06/21)
A novel series of dual orexin receptor antagonists was prepared by heteroaromatic five-membered ring system replacement of the dimethoxyphenyl moiety contained in the tetrahydroisoquinoline core skeleton of almorexant. Thus, replacement of the dimethoxyph
