122134-92-3Relevant academic research and scientific papers
Synthesis of esters of para-hydroxy substituted α-trifluoromethylmandelic acids
Dyachenko, V. I.,Kolomietz, A. F.,Fokin, A. V.
, p. 511 - 513 (1995)
Methyl trifluoropiruvate in trifluoroacetic acid at 20 deg C rapidly C-hydroxyalkylates various phenols at the para-positions to afford the corresponding esters of para-hydroxy substituted α-trifluoromethylmandelic acids. - Keywords: methyl trifluoropiruvate, trifluoroacetic acd, phenol, 3-cresol, 2,3-xylenol, 2,5-xylenol, thymol, C-hydroxyalkylation
