1221402-69-2Relevant academic research and scientific papers
Asymmetric Michael addition of cyclohexanone or cyclopentanone to chalcones catalyzed by an L-proline-based organic phosphane
Liu, Lingyan,Zhu, Yunna,Huang, Kaimeng,Chang, Weixing,Li, Jing
, p. 2634 - 2645 (2013)
An organophosphane catalyst derived from L-proline was shown to be a very effective catalyst for asymmetric Michael addition reactions of various chalcones to cyclic ketones including both cyclohexanone and cyclopentanone. The corresponding adducts could
Highly enantioselective Michael addition of cyclopentanone with chalcones via novel di-iminium mechanism
Wang, Junfeng,Wang, Xin,Ge, Zemei,Cheng, Tieming,Li, Runtao
supporting information; experimental part, p. 1751 - 1753 (2010/07/06)
The highly efficient asymmetric Michael addition reactions of cyclopentanone with chalcones were catalyzed by a simple and commercially available chiral 1,2-diaminocyclohexane-hexanedioic acid, and exhibited good yields (up to 92%) and excellent enantioselectivities (up to 99% ee). A new di-iminium mechanism for the reaction was proposed.
