1221403-63-9

Basic information

• Product Name: C₂₆H₂₆N₄O₃
• CAS NO: 1221403-63-9
• Molecular Weight: 442.517
• Mol File: 1221403-63-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₆H₂₆N₄O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₆H₂₆N₄O₃(1221403-63-9)
• EPA Substance Registry System: C₂₆H₂₆N₄O₃(1221403-63-9)

Safety Data

• Hazardous Substances Data: 1221403-63-9(Hazardous Substances Data)

Upstream product

• 16114-47-9 3,5-dimethylisoxazole-4-boronic acid 
• 1221403-74-2 C₂₁H₂₀BrN₃O₂ 

Relevant articles and documents

Identification of piperazine-bisamide GHSR antagonists for the treatment of obesity

Piperazine-bisamide analogs were discovered as partial agonists of human growth hormone secretagogue receptor (GHSR) in a high throughput screen. The partial agonists were optimized for potency and converted into antagonists through structure-activity relationship (SAR) studies. The efforts also led to the identification of potent antagonist with favorable PK profile suitable as a tool compound for in vivo studies.