1221403-87-7 Usage
General Description
Methyl 2-(2-fluorophenyl)thiazole-4-carboxylate is a chemical compound that belongs to the thiazole carboxylates class. It is an ester formed from the condensation of 2-(2-fluorophenyl)thiazole-4-carboxylic acid with methanol. Methyl 2-(2-fluorophenyl)thiazole-4-carboxylate is commonly used in organic synthesis and pharmaceutical research due to its potential as a precursor for the synthesis of various bioactive molecules. Its unique structure and properties make it an important building block for the development of pharmaceutical drugs and agrochemicals. Additionally, it can also be used as a research tool in medicinal chemistry and chemical biology for the investigation of various biological processes and pathways.
Check Digit Verification of cas no
The CAS Registry Mumber 1221403-87-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,1,4,0 and 3 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1221403-87:
(9*1)+(8*2)+(7*2)+(6*1)+(5*4)+(4*0)+(3*3)+(2*8)+(1*7)=97
97 % 10 = 7
So 1221403-87-7 is a valid CAS Registry Number.
1221403-87-7Relevant articles and documents
Identification of piperazine-bisamide GHSR antagonists for the treatment of obesity
Yu, Ming,Lizarzaburu, Mike,Beckmann, Holger,Connors, Richard,Dai, Kang,Haller, Katrin,Li, Cong,Liang, Lingming,Lindstrom, Michelle,Ma, Ji,Motani, Alykhan,Wanska, Malgorzata,Zhang, Alex,Li, Leping,Medina, Julio C.
scheme or table, p. 1758 - 1762 (2010/07/05)
Piperazine-bisamide analogs were discovered as partial agonists of human growth hormone secretagogue receptor (GHSR) in a high throughput screen. The partial agonists were optimized for potency and converted into antagonists through structure-activity relationship (SAR) studies. The efforts also led to the identification of potent antagonist with favorable PK profile suitable as a tool compound for in vivo studies.
