1221497-65-9Relevant academic research and scientific papers
Tandem reactions of N′-(2-Alkynylbenzylidene)hydrazides with Silyl Enolates: A facile route to H -pyrazolo[5,1- a ]isoquinolines
Yu, Xingxin,Chen, Zhiyuan,Yang, Xiaodi,Wu, Jie
, p. 374 - 378 (2010)
A silver triflate-catalyzed tandem reaction of N′-(2- alkynylbenzylidene)hydrazide with silyl enolate is described, which generates the unexpected H-pyrazolo[5,1-a]isoquinolines in good to excellent yields. Intramolecular cyclization, nucleophilic addition, condensation, and aromatization may be involved in the reaction process.
