122151-25-1Relevant academic research and scientific papers
SYNTHESIS OF (S)-N-(BENZYLOXY)-4-ACETOXYMETHYL-2-AZETIDINONE, POTENTIAL INTERMEDIATE FOR CARBAPENEM ANTIBIOTICS, BY CHEMOMICROBIOLOGICAL APPROACH
Yamada, Haruo,Sugiyama, Hajime,Kajiwara, Masahiro
, p. 2841 - 2844 (2007/10/02)
(R)-Ethyl 4-t-butoxy-3-hydroxybutanoate, which was prepared by baker's yeast reduction of ethyl 4-t-butoxy-3-oxobutanoate, was converted to (R)-3-hydroxybutyrolactone.After cleavage of the lactone ring with N-benzyloxyamine, β-lactam cyclization of the hy
