122168-40-5 Usage
Description
Gymnemic acid I is a triterpene glycoside that has been found in G. sylvestre and has antihyperglycemic activities. It inhibits glucose-induced phosphorylation of serine 70 on S6 kinase (S6K1) and serine 2448 on mTOR, caspase-3 activity, and apoptosis, as well as increases autophagy in MIN-6 pancreatic β cells when used at a concentration of 5 μg/ml. Gymnemic acid I has been used as a reference compound to compare the potency of plant-derived sweet taste inhibitors.
Uses
(+)-Gymnemic Acid I is one of the components extracted from the leaves of Gymnema sylvestre, known for inhibitory acitivity against glucose absorption. However, (+)-Gymnemic Acid I lacks this activity, unlike other forms of gymnemic acids.
Check Digit Verification of cas no
The CAS Registry Mumber 122168-40-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,2,1,6 and 8 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 122168-40:
(8*1)+(7*2)+(6*2)+(5*1)+(4*6)+(3*8)+(2*4)+(1*0)=95
95 % 10 = 5
So 122168-40-5 is a valid CAS Registry Number.
InChI:InChI=1/C43H66O14/c1-10-21(2)36(53)57-34-33(50)43(20-54-22(3)45)24(17-38(34,4)5)23-11-12-26-39(6)15-14-28(55-37-31(49)29(47)30(48)32(56-37)35(51)52)40(7,19-44)25(39)13-16-41(26,8)42(23,9)18-27(43)46/h10-11,24-34,37,44,46-50H,12-20H2,1-9H3,(H,51,52)/b21-10+/t24-,25+,26+,27-,28-,29-,30-,31+,32-,33-,34-,37+,39-,40-,41+,42+,43-/m0/s1
