122169-09-9

Upstream product

• 132335-19-4 10-Phenylphenanthrene-2',9-dicarboxaldehyde 
• 97306-07-5 trans-9-acetoxy-10-bromo-9,10-dihydrobenzochrysene 
• 122048-24-2 12-(3-carbomethoxy-2-propenyl)-12-hydroxy-9,10,11,12-tetrahydrotriphenylene 
• 122048-54-8 (9S,10S)-10-Bromo-9,10-dihydro-benzo[g]chrysen-9-ol 
• 122048-28-6 11-hydroxy-11,12,13,14-tetrahydrobenzochrysene 
• 122048-27-5 13,14-dihydrobenzochrysen-11(12H)-one 
• 122048-29-7 13,14-dihydrobenzochrysene 
• 68151-17-7 3,4-dihydrotriphenylen-1(2H)-one 
• 196-78-1 benzo[g]chrycene 
• 122048-55-9 (S)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (9R,10R)-10-bromo-9,10-dihydro-benzo[g]chrysen-9-yl ester 
• 122048-55-9 (S)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (9S,10S)-10-bromo-9,10-dihydro-benzo[g]chrysen-9-yl ester 
• 97306-06-4 3,4-dihydrobenzochrysene 
• 97306-05-3 1-hydroxy-1,2,3,4-tetrahydrobenzochrysene 
• 97306-04-2 1-oxo-1,2,3,4-tetrahydrobenzochrysene 

Downstream Products

• 132335-20-7 1a,13c-Dihydrobenzo<11,12>chryseno<5,6-b>azirine 

Relevant academic research and scientific papers

SYNTHESIS OF BENZOCHRYSENE, BENZOCHRYSENE 9,10-OXIDE AND BENZOCHRYSENE 1,2:9,10-DIOXIDE

Benzochrysene has been synthesised and used in the preparation of the K-region arene oxide, benzochrysene 9,10-oxide.Attempts to synthesise the fjord region arene oxide, benzochrysene 1,2-oxide, were unsuccessful but a fjord region diarene oxide, benzochrysene 1,2:9,10-dioxide has been obtained.

Arene Imine Derivatives of Chrysene and of Benzochrysene: 1a,11c-Dihydrochrysenoazirine and 1a,13c-Dihydrobenzochrysenoazirine

The syntheses of the K-imines (which are also benzo-bay-region derivatives) of chrysene (1) and benzochrysene (2) are described.The preparation of 1a,11c-dihydrochrysenoazirine (5) was accomplished by treatment of 1a,11c-dihydrochrysenooxirene (4) with sodium azide, and the mixture of trans-azido-alcohols 6 and 7, so formed, was either cyclized with triethyl phosphite, or converted into E-6-azido-5-chloro-5,6-dihydrochrysene (8) followed by lithium aluminium hydride reduction.The synthesis of 1a,13c-dihydrobenzochrysenoazirine (12) included the transformation of the corresponding oxide 11 into a mixture of E-9-azido-9,10-dihydrobenzochrysen-10-ol (13) and E-10-azido-9,10-dihydrobenzochrysen-9-ol (14), and reaction with tri-n-butylphosphine to give a mixture of Staudinger adducts 15 and 16 that underwent thermal decomposition into 12 upon heating in boiling dichloromethane.

Synthesis of Optically Active Fjord-Region 11,12-Diol 13,14-Epoxides and the K-Region 9,10-Oxide of the Carcinogen Benzochrysene

Optically pure enantiomers of the diastereomeric pair of benzochrysene-11,12-diol 13,14-epoxides (Scheme VI) were synthesized from (11R,12R)- and (11S,12S)-dihydroxy-11,12-dihydrobenzochrysenes (16(R,R) and 16(S,S)).Two routes were employed to synth