1222-69-1Relevant academic research and scientific papers
Formation of Furan Derivatives from Phenacyl Bromides and Sodium Telluride; Attempted Extension to Coumarin Synthesis
Padmanabhan, Seetharamaiyer,Ogawa, Takuji,Suzuki, Hitomi
, p. 2114 - 2116 (1989)
The enolates, generated from phenacyl bromides by sodium telluride, yield 2,4-diarylfurans in addition to the expected dehalogenation products.No 1,4-dicarbonyl compounds could be isolated even in the presence of excess oxidizing agent, copper(II) chloride.Condensation of 2-(methoxymethoxy)arenecarbaldehydes with ethyl bromoacetate in the presence of sodium telluride gave the expected α,β-unsaturated esters which resisted cyclization to yield the desired coumarin derivatives.Attempted intramolecular Reformatsky-type reaction of 2-(bromoacetoxy)benzaldehyde gave only 6,12-epoxy-6H,12H-dibenzo-dioxocin as the major product.
Access to Benzylic Quaternary Carbons from Aromatic Ketones
Li, You,Han, Jingpeng,Luo, Han,An, Qiaoyu,Cao, Xiao-Ping,Li, Baosheng
supporting information, p. 6050 - 6053 (2019/08/26)
The construction of benzylic all-carbon quaternary stereocenters, which are ubiquitous in biomolecules and drugs, is a task of high practical significance. Herein, we disclose a highly efficient one-pot method of constructing all-carbon quaternary structu
Synthesis and properties of Z-1, 3-bis- (aryl)-4-bromo-2-buten-1-ones
Potikha,Turelik,Kovtunenko
experimental part, p. 1184 - 1189 (2010/05/18)
Bromination of 1, 3-bis(aryl)-2-buten-1-ones by N-bromosuccinimide in anhydrous carbon tetrachloride gives Z-1, 3-bis(aryl)-4-bromo-2-buten-1-ones. The effect of the nature of substituent in the benzene ring on the course of a reaction with nucleophiles h
