1222097-05-3Relevant academic research and scientific papers
Highly chemo- and enantioselective synthesis of 3-Allyl-3-aryl oxindoles via the direct palladium-catalyzed α-arylation of amides
Luan, Xinjun,Wu, Linglin,Drinkel, Emma,Mariz, Ronaldo,Gatti, Michele,Dorta, Reto
, p. 1912 - 1915 (2010)
Figure presented A new NHC·Pd-catalyzed asymmetric α-arylation of amides is reported that gives direct access to synthetically valuable, allylated oxindoles with quaternary carbon centers. The reaction is made possible by the introduction of a new chiral NHC ligand. The palladium complexes derived therefrom combine excellent reactivity with high chemo- and enantioselectivity for the title transformation.
