1222099-58-2Relevant academic research and scientific papers
Asymmetric total synthesis of the caspase-1 inhibitor (-)-berkeleyamide A
Kulkarni, Swapnil J.,Pedduri, Yakambram,Chittiboyina, Amar G.,Avery, Mitchell A.
supporting information; experimental part, p. 3113 - 3116 (2010/07/15)
The asymmetric total synthesis of (-)-berkeleyamide A (1), a naturally occurring caspase-1 inhibitor, has been achieved by employing Evans' syn-aldol reaction of N-acyl-(4R)-benzyl oxazolidin-2-one 3 as the key step.
