1222374-83-5

Basic information

• Product Name: C₁₁H₁₆N₂O₂S
• CAS NO: 1222374-83-5
• Molecular Weight: 240.326
• Mol File: 1222374-83-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₁H₁₆N₂O₂S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₁H₁₆N₂O₂S(1222374-83-5)
• EPA Substance Registry System: C₁₁H₁₆N₂O₂S(1222374-83-5)

Safety Data

• Hazardous Substances Data: 1222374-83-5(Hazardous Substances Data)

Upstream product

• 15806-29-8 2,4-dimethoxyphenethylamine 
• 1147550-11-5 ammonium thiocyanate 

Downstream Products

• 1222375-42-9 C₁₄H₁₇N₃O₃S 

Relevant articles and documents

Evaluation of 2-thioxo-2,3,5,6,7,8-hexahydropyrimido[4,5-d]pyrimidin-4(1H)-one analogues as GAA activators

Pompe disease is a lysosomal storage disease (LSD) caused by a deficiency in the lysosomal enzyme acid alpha-glucosidase. In several LSDs, enzyme inhibitors have been used as small molecule chaperones to facilitate and increase the translocation of mutant protein from the endoplasmic reticulum to the lysosome. Enzyme activators with chaperone activity would be even more desirable as they would not inhibit the enzyme after translocation and might potentiate the activity of the enzyme that is successfully translocated. Herein we report our initial findings of a new series of acid alpha-glucosidase activators.