122246-73-5Relevant academic research and scientific papers
Carbinolamine Equivalents in the 8-Amino-tetrahydroisoquinoline Series
Moehrle, Hans,Biegholdt, Martin
, p. 287 - 291 (2007/10/02)
Hg(II)-EDTA dehydrogenations of the 8-aminosubstituted tetrahydroisoquinolines 1 and 2 do not yield the expected pure carbinolamines, but the dimers 7 and 8 in an intermolecular reaction.The acetylation of the dimers or of the corresponding iminium salts 5 and 6, respectively, generates the tricyclic primary products 9 and 13, which show ring cleavage when the reaction time is prolongated.
