122273-74-9Relevant academic research and scientific papers
Photoredox-Catalyzed Ketyl-Olefin Coupling for the Synthesis of Substituted Chromanols
Fava, Eleonora,Nakajima, Masaki,Nguyen, Anh L. P.,Rueping, Magnus
, p. 6959 - 6964 (2016/08/30)
A visible light photoredox-catalyzed aldehyde olefin cyclization is reported. The method represents a formal hydroacylation of alkenes and alkynes and provides chromanol derivatives in good yields. The protocol takes advantage of the double role played by trialkylamines (NR3) which act as (i) electron donors for reducing the catalyst and (ii) proton donors to activate the substrate via a proton-coupled electron transfer.
Reductions by hydrides and hydroboration. The stereoselectivity of new access methods to 3-arylmethyl-4-chromanones (homoisoflavone derivatives)
Gomis,Kirkiacharian
, p. 1849 - 1858 (2007/10/02)
The reduction of 3-arylmethyl-4-chromanones by sodium borohydride, lithium tri-tert-butoxyaluminum hydride and hydroboration followed by oxydation of 3-benzyl-4-hydroxy-coumarines lead to mixtures of Cis and Trans diastereoisomers of 3-arylmethyl-4-chroma
Reduction par les hydrures : synthese et stereochimie des benzyl-3 chromannols-4
Gomis, M.,Kirkiacharian, B.S.,Likforman, J.,Mahuteau, J.
, p. 585 - 590 (2007/10/02)
Reduction of 3-arylidene 4-chromannones with lithium aluminium hydride leads in straightforward fashion to two 3-arylmethyl 4-chromannols diastereoisomers, for each derivative.Stereochemistry of 3-benzyl 4-chromanols is resolved by 1H and 13C NMR.Major trans compounds were obtained.
