1222767-12-5

Basic information

• Product Name: N-(5-methyl-1,2-oxazol-3-yl)-2-[1-({3-[6-(morpholin-4-yl)pyridin-3-yl]phenyl}methyl)-1H-indole-3-sulfonyl]acetamide
• CAS NO: 1222767-12-5
• Molecular Weight: 571.657
• Mol File: 1222767-12-5.mol

Chemical Properties

• CAS DataBase Reference: N-(5-methyl-1,2-oxazol-3-yl)-2-[1-({3-[6-(morpholin-4-yl)pyridin-3-yl]phenyl}methyl)-1H-indole-3-sulfonyl]acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(5-methyl-1,2-oxazol-3-yl)-2-[1-({3-[6-(morpholin-4-yl)pyridin-3-yl]phenyl}methyl)-1H-indole-3-sulfonyl]acetamide(1222767-12-5)
• EPA Substance Registry System: N-(5-methyl-1,2-oxazol-3-yl)-2-[1-({3-[6-(morpholin-4-yl)pyridin-3-yl]phenyl}methyl)-1H-indole-3-sulfonyl]acetamide(1222767-12-5)

Safety Data

• Hazardous Substances Data: 1222767-12-5(Hazardous Substances Data)

Upstream product

• 54466-88-5 2-[(1H-indol-3-yl)sulfanyl]acetic acid 
• 1321092-72-1 methyl (1H-indol-3-ylsulfanyl)acetate 
• 450352-01-9 2-((1H-indol-3-yl)thio)-N-(5-methylisoxazol-3-yl)acetamide 
• 850932-37-5 C₁₄H₁₃N₃O₄S 
• 904326-93-8 [6-(morpholin-4-yl)pyridin-3-yl]boronic acid 
• 1222799-84-9 2-((1-(3-bromobenzyl)-1H-indol-3-yl)sulfonyl)-N-(5-methylisoxazol-3-yl)acetamide 
• 120-72-9 indole 

Relevant articles and documents

INDOLE COMPOUNDS AS POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC RECEPTOR

In one aspect, the invention relates to indole compounds, derivatives thereof, and related compounds, which are useful as positive allosteric modulators of the muscarinic acetylcholine receptor M1 (mAChR M1); synthetic methods for ma

Discovery and optimization of a novel, selective and brain penetrant M 1 positive allosteric modulator (PAM): The development of ML169, an MLPCN probe

This Letter describes a chemical lead optimization campaign directed at VU0108370, a weak M1 PAM hit with a novel chemical scaffold from a functional HTS screen within the MLPCN. An iterative parallel synthesis approach rapidly established SAR