1222802-30-3Relevant academic research and scientific papers
Switching from (R)- to (S)-selective chemoenzymatic DKR of amines involving sulfanyl radical-mediated racemization
El Blidi, Lahssen,Vanthuyne, Nicolas,Siri, Didier,Gastaldi, Stephane,Bertrand, Michele P.,Gil, Gerard
supporting information; experimental part, p. 4165 - 4168 (2010/11/02)
Chemoenzymatic dynamic kinetic resolution (DKR) of amines involving sulfanyl radical-induced racemization happened to be the very first switchable DKR process allowing the synthesis of either (R)- or (S)-amides, in good yield and high enantiomeric excess,
Proteases screening for the kinetic resolution of amines with N-acyl α-amino acid trifluoromethyl esters: automated docking approach of binding energies using Subtilisin Novo as a prototype for serine proteases
Bottalla, Anne-Lise,Queyroy, Severine,Azzi-Schue, Nadia,Vanthuyne, Nicolas,Gastaldi, Stephane,Bertrand, Michele P.,Gil, Gerard
experimental part, p. 2823 - 2834 (2010/03/30)
The screening of a panel of 17 proteases resulted in the selection of 4 serine proteases for the resolution of 3-amino-1-phenylbutane. The latter were used to determine the best acyl donor from a series of N-acyl α-amino acid trifluoroethyl esters selecte
