122293-99-6

Upstream product

• 122293-97-4 ethyl -6-amino-4-<(2-hydroxy-1-methyl-2-phenylethyl)amino>-5-nitropyridine-2-carbamate 
• 492-41-1 (1R,2S)-norephedrine 
• 108-86-1 bromobenzene 
• 20562-66-7 Phenanthroline 
• 6506-86-1 ethyl (6-amino-4-chloro-5-nitropyridin-2-yl)carbamate 

Downstream Products

• 122332-18-7 ethyl <(S)-5-amino-1,2-dihydro-2-methyl-3-phenylpyrido<3,4-b>pyrazin-7-yl>carbamate 

Relevant academic research and scientific papers

Chiral ethyl [6-amino-4-[[12-(methoxymethylamino)-1-methyl-2-oxoethyl]amino]-5-nitro-2-pyridyl]carbamate

The present invention relates to compounds of the formula STR1 wherein each of R and R1 is a lower alkyl group having from 1 to 4 carbon atoms, which are useful as intermediates to make chiral ethyl (5-amino-1,2-dihydro-2-methyl-3-phenylpyrido[

New Anticancer Agents: Chiral Isomers of Ethyl 5-Amino-1,2-dihydro-2-methyl-3-phenylpyridopyrazine-7-carbamate

Racemic ethyl 5-amino-1,2-dihydro-2-methyl-3-phenylpyridopyrazine-7-carbamate (1a) has shown antitumor activity in a variety of in vivo experiments.The preparation of the R (9) and S (10) isomers gave compounds with significant differences in potency in several biological tests.