1222999-58-7

Basic information

• Product Name: 9-(6-aminopyridin-3-yl)-1-(4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one
• Synonyms: 9-(6-aminopyridin-3-yl)-1-(4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one
• CAS NO: 1222999-58-7
• Molecular Weight: 516.525
• Mol File: 1222999-58-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 9-(6-aminopyridin-3-yl)-1-(4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 9-(6-aminopyridin-3-yl)-1-(4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one(1222999-58-7)
• EPA Substance Registry System: 9-(6-aminopyridin-3-yl)-1-(4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one(1222999-58-7)

Safety Data

• Hazardous Substances Data: 1222999-58-7(Hazardous Substances Data)

Upstream product

• 206257-39-8 6-bromo-4-chloroquinoline-3-carboxylic acid ethyl ester 
• 193902-87-3 tert-butyl 4-(4-amino-2-(trifluoromethyl)phenyl)piperazine-1-carboxylate 

Downstream Products

• 1222998-36-8 Torin₁ 

Relevant articles and documents

METHOD OF BLOCKING TRANSMISSION OF MALARIAL PARASITE

The invention provides a method of blocking transmission of a Plasmodium parasite and a method of treating or preventing malaria comprising administering to an animal an effective amount of a first compound of formula I: wherein A, B, R1, R2, R10, and R11 are described herein, either alone or in combination with a second compound selected from elesclomol, NSC 174938, NVP-AUY922, Maduramicin, Narasin, Alvespimycin, Omacetaxine, Thiram, Zinc pyrithione, Phanquinone, Bortezomib, Salinomycin sodium, Monensin sodium, Dipyrithione, Dicyclopentamethylene-thiuram disulfide, YM155, Withaferin A, Adriamycin, Romidepsin, AZD-1 152-HQPA, CAY10581, Plicamycin, CUDC-101, Auranofin, Trametinib, GSK-458, Afatinib, and Panobinostat.