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1-Naphthylacetylspermine is a polyamine amide that functions as a potent inhibitor of spermidine uptake.

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  • Naspm Trihydrochloride,n-[3-[[4-[(3-aminopropyl)amino]butyl]amino]propyl]-1-naphthaleneacetamidetrihydrochloride

    Cas No: 122306-11-0

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  • 122306-11-0 Structure
  • Basic information

    1. Product Name: 1-naphthylacetylspermine
    2. Synonyms: 1-naphthylacetylspermine;N-[3-[[4-[(3-Aminopropyl)amino]butyl]amino]propyl]-1-naphthaleneacetamide;Naspm;NASPM trihydrochloride;2-(1-Naphtyl)-N-[3-[[4-[(3-aminopropyl)amino]butyl]amino]propyl]acetamide;N-[3-[4-(3-Aminopropylamino)butylamino]propyl]naphthalene-1-acetamide;C13674;N-[3-[[4-[(3-Aminopropyl)amino]butyl]amino]propyl]-1-naphthaleneacetamidetrihydrochloride
    3. CAS NO:122306-11-0
    4. Molecular Formula: C22H34N4O
    5. Molecular Weight: 370.53
    6. EINECS: N/A
    7. Product Categories: Amines;Aromatics;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals
    8. Mol File: 122306-11-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 608.9°Cat760mmHg
    3. Flash Point: 322.1°C
    4. Appearance: /
    5. Density: 1.062g/cm3
    6. Vapor Pressure: 9.01E-15mmHg at 25°C
    7. Refractive Index: 1.569
    8. Storage Temp.: Desiccate at +4°C
    9. Solubility: N/A
    10. PKA: 15.26±0.46(Predicted)
    11. CAS DataBase Reference: 1-naphthylacetylspermine(CAS DataBase Reference)
    12. NIST Chemistry Reference: 1-naphthylacetylspermine(122306-11-0)
    13. EPA Substance Registry System: 1-naphthylacetylspermine(122306-11-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: 22-24/25
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 122306-11-0(Hazardous Substances Data)

122306-11-0 Usage

Uses

Used in Pharmaceutical Industry:
1-Naphthylacetylspermine is used as a spermidine uptake inhibitor for its ability to block the absorption of spermidine, a polyamine involved in cell growth and proliferation. This property makes it a potential candidate for the development of therapeutic agents targeting conditions related to abnormal cell growth, such as cancer.

Check Digit Verification of cas no

The CAS Registry Mumber 122306-11-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,2,3,0 and 6 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 122306-11:
(8*1)+(7*2)+(6*2)+(5*3)+(4*0)+(3*6)+(2*1)+(1*1)=70
70 % 10 = 0
So 122306-11-0 is a valid CAS Registry Number.
InChI:InChI=1/C22H34N4O/c23-12-6-15-24-13-3-4-14-25-16-7-17-26-22(27)18-20-10-5-9-19-8-1-2-11-21(19)20/h1-2,5,8-11,24-25H,3-4,6-7,12-18,23H2,(H,26,27)

122306-11-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name Naspm trihydrochloride,N-[3-[[4-[(3-Aminopropyl)amino]butyl]amino]propyl]-1-naphthaleneacetamidetrihydrochloride

1.2 Other means of identification

Product number -
Other names 1-naphthylacetylspermine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:122306-11-0 SDS

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