122331-42-4

Basic information

• Product Name: Ethanone, 1-[(5S)-4,5-dihydro-3-phenyl-5-isoxazolyl]-
• CAS NO: 122331-42-4
• Molecular Formula: C11H11NO2
• Molecular Weight: 189.214
• Mol File: 122331-42-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-[(5S)-4,5-dihydro-3-phenyl-5-isoxazolyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[(5S)-4,5-dihydro-3-phenyl-5-isoxazolyl]-(122331-42-4)
• EPA Substance Registry System: Ethanone, 1-[(5S)-4,5-dihydro-3-phenyl-5-isoxazolyl]-(122331-42-4)

Safety Data

• Hazardous Substances Data: 122331-42-4(Hazardous Substances Data)

Upstream product

• 121523-84-0 (αS)-threo-α-methyl-3-phenyl-2-isoxazoline-5-methanol 
• 54606-00-7 5-acetyl-4,5-dihydro-3-phenylisoxazole 
• 122331-40-2 (1R)-1-<(5S)-4,5-dihydro-3-phenyl-5-isoxazolyl>ethanol 

Downstream Products

• 121523-84-0 (αS)-threo-α-methyl-3-phenyl-2-isoxazoline-5-methanol 
• 122331-40-2 (1R)-1-<(5S)-4,5-dihydro-3-phenyl-5-isoxazolyl>ethanol 

Relevant articles and documents

Effect of different strains of yeast on stereocontrolled reduction of 5-acetylisoxazolines

The stereocontrolled reduction of 3-aryl-5-acetylisoxazolines (1) to the corresponding alcohols (2 and 3) in the presence of four different yeast strains, recognized as Baker's yeast (commercial), Candida krusei (ATCC 14243), Pichia farinosa (NRRL Y110) and Sacchromyces sp. (soil isolate) have been attempted. The C. krusei was found to be diastereoselective for the (R)-1 while the Sacchromyces sp. led to complete reduction to yield the RS- and SS-alcohol in 1:1 ratio at 10 g/L scale.