122333-28-2

Upstream product

• 121911-10-2 (3R)-3-fluoro-1(R)-<(4-methylphenyl)sulfinyl>-5-hexen-2-one 
• 121911-11-3 (3S)-3-fluoro-1(R)-<(4-methylphenyl)sulfinyl>-5-hexen-2-one 
• 121961-08-8 (4S,5S)-4-fluoro-5-hydroxy-6-<(R)-(4-methylphenyl)sulphinyl>-hex-1-ene 

Downstream Products

• 122406-17-1 (R)-2-Phenyl-propionic acid (1S,2S)-2-fluoro-1-p-tolylsulfanylmethyl-pent-4-enyl ester 
• 122333-29-3 (S)-2-Phenyl-propionic acid (1S,2S)-2-fluoro-1-p-tolylsulfanylmethyl-pent-4-enyl ester 

Relevant academic research and scientific papers

Homochiral 2,5-Disubstituted 3-Fluorotetrahydrofurans carrying differently Functionalized Ring Appendages

With (R)-1-sulphinyl-3-fluoropropan-2-one (1) as starting material a multistep approach is described for the asymmetric synthesis of various 3-fluorotetrahydrofurans of type (7)-(12) which carry differently functionalized 2- and 5-methyl groups.