1223405-93-3

Upstream product

• 53008-65-4 methyl 2,3,4-tri-O-benzyl-D-glucopyranoside 
• 3740-52-1 2-(2-nitrophenyl)acetic acid 

Downstream Products

• 53008-65-4 methyl 2,3,4-tri-O-benzyl-D-glucopyranoside 
• 151992-85-7 ethyl 2-O-benzoyl-3-O-benzyl-4-O-(4-methoxybenzyl)-1-thio-β-D-glucopyranoside 

Relevant academic research and scientific papers

A new method testing the orthogonality of different protecting groups

A new test was elaborated to identify a new set of orthogonal protecting groups. With the developed method eight different protecting groups were tested under various deprotection conditions and the complex reaction mixtures were analysed by HPLC. The dev

(2-Nitrophenyl)acetyl: A new, selectively removable hydroxyl protecting group

Figure presented The utility of the (2-nitrophenyl)acetyl (NPAc) group for the protection of hydroxyl functions is reported. (2-Nitrophenyl)acetates are readily prepared starting from the commercially available, inexpensive (2-nitrophenyl)acetic acid, and these esters are stable under a series of common carbohydrate transformations. The NPAc group can be removed selectively using Zn and NH4Cl without affecting a series of common protecting groups. This new protecting group is orthogonal with the commonly used tert-butyldimethylsilyl, levulinoyl, 9-fluorenylmethoxycarbonyl, naphthylmethyl, and p-methoxybenzyl groups.